Basic Information
LncRNA/CircRNA Name | UCA1 |
Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
Region | GRCh38_19:15828206-15836326 |
Ensemble | ENSG00000214049 |
Refseq | NR_015379 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | renal cancer |
ICD-0-3 | C64.9 |
Methods | qPCR, Western blot |
Sample | renal cancer tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | UCA1-miR-182-5p-DLL4 axis is involved in proliferation and progression of renal cancer. |
Pubmed ID | 31996265 |
Year | 2020 |
Title | Long non-coding RNA UCA1 promotes malignant phenotypes of renal cancer cells by modulating the miR-182-5p/DLL4 axis as a ceRNA |
External Links
Links for UCA1 | GenBank HGNC NONCODE |
Links for renal cancer | OMIM COSMIC |