Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | adrenocortical carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | ACC tissues,cell line(SW-13) |
| Expression Pattern | up-regulated |
| Function Description | Overexpression of UCA1 facilitated the growth of ACC cells, which suggested the potential oncogenic function of UCA1 in ACC. |
| Pubmed ID | 30935924 |
| Year | 2019 |
| Title | Long non-coding RNA UCA1 promoted the growth of adrenocortical cancer cells via modulating the miR-298-CDK6 axis. |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for adrenocortical carcinoma | OMIM COSMIC |