Basic Information
LncRNA/CircRNA Name | UCA1 |
Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
Region | GRCh38_19:15828206-15836326 |
Ensemble | ENSG00000214049 |
Refseq | NR_015379 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR etc. |
Sample | HCC tissues |
Expression Pattern | up-regulated |
Function Description | The expression of lncRNA-UCA1 and C-JUN was positive in 91.4%HCC patients with strong discriminating power between HCC and healthy subjects and CHC patients as well. The median follow up period was 29 months. The survival analysis showed that both lncRNA-UCA1 and C-JUN were independent prognostic factors. |
Pubmed ID | 27215316 |
Year | 2016 |
Title | Association of long noncoding RNA and c-JUN expression in hepatocellular carcinoma. |
External Links
Links for UCA1 | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |