Basic Information
| LncRNA/CircRNA Name | UICC |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | mircoarray, qPCR, Western blot, RIP |
| Sample | cervical cancer tissues, cell lines(Caski, SiHa, HeLa, Ms751, C33a) |
| Expression Pattern | up-regulated |
| Function Description | we identified a novel lncRNA termed lncRNA upregulated in cervical cancer (lnc-UICC) that was highly expressed in cervical cancer tissue. lnc-UICC expression in cervical cancer was associated with FIGO stage, lymph node metastasis and prognosis. lnc-UICC overexpression inhibited the apoptosis of HeLa cells. lnc-UICC promotes cell growth in vitro and in vivo. |
| Pubmed ID | 30094092 |
| Year | 2018 |
| Title | A Novel Positive Feedback Regulation Between Long Noncoding RNA UICC and IL-6/STAT3 Signaling Promotes Cervical Cancer Progression. |
External Links
| Links for UICC | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |