Basic Information
| LncRNA/CircRNA Name | UPK1A-AS1 |
| Synonyms | NA |
| Region | GRCh38_19:35667948-35673291 |
| Ensemble | ENSG00000226510 |
| Refseq | NR_046420 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay etc. |
| Sample | ESCC tissues and adjacent normal tissues, cell lines (EC109, EC9706, KYSE30 and KYSE150,SHEE) |
| Expression Pattern | down-regulated |
| Function Description | UPK1A-AS1 Expression Is Significantly Downregulated in ESCC Tissues and Cell Lines.UPK1A-AS1/miR-1248 axis serves as a novel regulatory axis in ESCC progression. |
| Pubmed ID | 32368143 |
| Year | 2020 |
| Title | Restoration of UPK1A-AS1 Expression Suppresses Cell Proliferation, Migration, and Invasion in Esophageal Squamous Cell Carcinoma Cells Partially by Sponging microRNA-1248 |
External Links
| Links for UPK1A-AS1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |