Basic Information
| LncRNA/CircRNA Name | URRCC |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Microarray, Western blot, Luciferase reporter assay |
| Sample | ccRCC tissues,cell lines (A498, 786-O, CaKi-1, ACHN,769-P,OSRC-2,HK-2) |
| Expression Pattern | up-regulated |
| Function Description | The microarray analysis and qRT-PCR identified a new lncRNA, URRCC, whose expression is upregulated in RCC samples and associated with poor prognosis, leading to promote ccRCC cell proliferation and invasion. |
| Pubmed ID | 30953521 |
| Year | 2019 |
| Title | A positive feed-forward loop between LncRNA-URRCC and EGFL7/P-AKT/FOXO3 signaling promotes proliferation and metastasis of clear cell renal cell carcinoma. |
External Links
| Links for URRCC | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |