Basic Information
| LncRNA/CircRNA Name | VELUCT |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | actinomycin D | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | RNA-seq, qPCR, RNAi, Northern blot etc. |
| Sample | cell lines (NCI-H460, NCI-H1944 and NCI-H1437) |
| Expression Pattern | differential expression |
| Function Description | Despite its extremely low abundance, loss-of-function of VELUCT with three independent experimental approaches in three different lung cancer cell lines led to a significant reduction of cell viability. In summary, the extremely low abundant lncRNA VELUCT is essential for regulation of cell viability in several lung cancer cell lines. |
| Pubmed ID | 28160600 |
| Year | 2017 |
| Title | The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance |
External Links
| Links for VELUCT | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |