Basic Information
| LncRNA/CircRNA Name | CASC2 |
| Synonyms | CASC2, C10orf5 |
| Region | GRCh38_10:118046279-118210153 |
| Ensemble | ENSG00000177640 |
| Refseq | NR_026939 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | cell lines (143B, U.2 OS, KHOS.240S, D22, Saos.2, HOS and MG.63,hFOB) |
| Expression Pattern | down-regulated |
| Function Description | CASC2 transduction may decrease proliferation, migration and invasion of osteosarcoma cell lines whereas knockdown of CASC2 displayed opposing effects.Patients with low CASC2 levels were predicted to have a poor survival. |
| Pubmed ID | 29257211 |
| Year | 2017 |
| Title | The long noncoding RNA cancer susceptibility candidate 2 inhibits tumor progression in osteosarcoma. |
External Links
| Links for CASC2 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |