Basic Information
| LncRNA/CircRNA Name | XIAP-AS1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000237331 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RIP, Western blot |
| Sample | gastric cell lines (Bgastric cancer823, Sgastric cancer7901, MKN28, AGS, Mgastric cancer803) |
| Expression Pattern | up-regulated |
| Function Description | In conclusion, our results indicate that XIAP-AS1 is involved in XIAP transcription by interacting with Sp1. Additionally, XIAP-AS1 is a potential target for TRAIL-induced apoptosis in gastric cancer cells.However, there was no significant correlation between the levels of XIAP-AS1 and survival probability (P = 0.07). |
| Pubmed ID | 28792527 |
| Year | 2017 |
| Title | The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells. |
External Links
| Links for XIAP-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |