Basic Information
| LncRNA/CircRNA Name | XIST |
| Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
| Region | GRCh38_X:73820651-73852753 |
| Ensemble | ENSG00000229807 |
| Refseq | NR_001564 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot, Luciferase reporter assay, etc. |
| Sample | cervical cancer tissues, cell lines (Hela, Caski, C4-1, Siha, GH329) |
| Expression Pattern | up-regulated |
| Function Description | XIST upregulated Fus through competitively binding with miR-200a. patients with high expression of XIST had a lower survival rate than those with low expression of XIST |
| Pubmed ID | 29909347 |
| Year | 2018 |
| Title | LncRNA XIST accelerates cervical cancer progression via upregulating Fus through competitively binding with miR-200a. |
External Links
| Links for XIST | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |