Basic Information
| LncRNA/CircRNA Name | XLOC_006390 |
| Synonyms | lnc-HOXA13-1, XLOC_006390, linc-HOXA11 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot etc. |
| Sample | cervical cancer tissues, cell lines (SiHa, HeLa, Caski, C4-1 and C-33a) |
| Expression Pattern | up-regulated |
| Function Description | XLOC_006390 is also increased in cervical cancer, and upregulation of lncRNA XLOC_006390 contributes to cervical cancer metastasis. XLOC_006390 promotes cervical cancer cell growth and metastasis through the regulation of SET8, at least partly, which indicate the critical roles of XLOC_006390 and SET8 in cervical cancer progression and metastasis. |
| Pubmed ID | 28534991 |
| Year | 2017 |
| Title | Long non-coding RNA XLOC_006390 promotes cervical cancer proliferation and metastasis through the regulation of SET domain containing 8. |
External Links
| Links for XLOC_006390 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |