Basic Information
| LncRNA/CircRNA Name | XLOC_032768 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | Cisplatin | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | qPCR, Western blot etc. |
| Sample | renal tissues,cell line (HK-2) |
| Expression Pattern | differential expressed |
| Function Description | The overexpression of XLOC_032768 significantly inhibited the cisplatin-induced apoptosis and inflammatory response in HK-2 cells and mouse exposed to cisplatin.RNA sequencing analysis further confirmed that XLOC_032768 could regulate tumor necrosis factor (TNF)-? in the cisplatin-induced apoptosis of HK-2 cells in trans-manner. |
| Pubmed ID | 32278129 |
| Year | 2020 |
| Title | Novel lncRNA XLOC_032768 alleviates cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells through TNF-?. |
External Links
| Links for XLOC_032768 | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell cancer | OMIM COSMIC |