Basic Information
| LncRNA/CircRNA Name | CASC21 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000253929 |
| Refseq | NR_117099 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-PCR, Western blot |
| Sample | colorectal cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | CASC21 functions as a ceRNA that plays an oncogenic role in the progression of colorectal cancer by regulating the miR-7-5p/YAP1 axis. LncRNA CASC21 might be a potential target for therapy of colorectal cancer. |
| Pubmed ID | 31731190 |
| Year | 2020 |
| Title | Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis |
External Links
| Links for CASC21 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |