Basic Information
| LncRNA/CircRNA Name | CASC2a |
| Synonyms | CASC2, C10orf5 |
| Region | GRCh38_10:118046279-118210153 |
| Ensemble | ENSG00000177640 |
| Refseq | NR_026939 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | urothelial cancer |
| ICD-0-3 | NA |
| Methods | RNA-seq, qPCR |
| Sample | Tumor tissues |
| Expression Pattern | down-regulated |
| Function Description | CASC2a was down-regulated in UCB tissues, and was highly negatively correlated with the pT, pN, tumor size, and lymphovascular invasion (LVI). |
| Pubmed ID | 29358570 |
| Year | 2018 |
| Title | Long Non-Coding RNA Cancer Susceptibility Candidate 2a (CASC2a) Is a Marker of Early Recurrence After Radical Cystectomy in Patients with Urothelial Carcinoma of the Bladder. |
External Links
| Links for CASC2a | GenBank HGNC NONCODE |
| Links for urothelial cancer | OMIM COSMIC |