Basic Information
| LncRNA/CircRNA Name | ZEB1-AS1 |
| Synonyms | NA |
| Region | GRCh38_10:31206278-31320447 |
| Ensemble | ENSG00000237036 |
| Refseq | NR_024284 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Luciferase reporter assay, RIP, Western blot |
| Sample | bladder tissues,cell lines(SW780, BIU, 5637, J82, T24, TCC-SUP, UM-UC3) |
| Expression Pattern | up-regulated |
| Function Description | Moreover, the oncogenic long non-coding RNA ZEB1-AS1 was highly expressed in BLCA and positively correlated tumor grade, high TNM stage, and reduced survival of patients with BLCA. |
| Pubmed ID | 30823924 |
| Year | 2019 |
| Title | Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-?1 in bladder cancer cells. |
External Links
| Links for ZEB1-AS1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |