Basic Information
| LncRNA/CircRNA Name | ZEB2-AS1 |
| Synonyms | NA |
| Region | GRCh38_2:144518097-144521477 |
| Ensemble | ENSG00000238057 |
| Refseq | NR_040248 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc |
| Sample | NSCLC tissues and matched adjacent tissue, cell lines (A549, NCI-H1650,HCC827) |
| Expression Pattern | up-regulated |
| Function Description | Subsequently, the ZEB2-AS1 level in A549 cells treated with different doses of IL-6 for different time points was determined. After A549 cells were treated with different doses of IL-6, wound closure assays were performed to assess the migration of cells. |
| Pubmed ID | 32329850 |
| Year | 2020 |
| Title | IL-6 stimulates lncRNA ZEB2-AS1 to aggravate the progression of non-small cell lung cancer through activating STAT1 |
External Links
| Links for ZEB2-AS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |