Basic Information
| LncRNA/CircRNA Name | CASC8 |
| Synonyms | cancer susceptibility candidate 8 |
| Region | GRCh38_8:127289817-127482139 |
| Ensemble | ENSG00000246228 |
| Refseq | NR_024393 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Western blot, etc. |
| Sample | bladder cancer tissues, cell lines (SW780, J82, UMUC3,T24, 5637 ) |
| Expression Pattern | down-regulated |
| Function Description | Overexpression of CASC8 remarkably suppressed the bladder cancer cell proliferation. |
| Pubmed ID | 28759252 |
| Year | 2017 |
| Title | Long Noncoding RNA Cancer Susceptibility Candidate 8 Suppresses the Proliferation of Bladder Cancer Cells via Regulating Glycolysis. |
External Links
| Links for CASC8 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |