Basic Information
| LncRNA/CircRNA Name | ZFAS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, etc. |
| Sample | blood |
| Expression Pattern | down-regulated |
| Function Description | while ZFAS1 level was only correlated with TNM stage (p=0.005 in TEPs, p=0.044 in plasma). Our data suggested that EGFRvIII can also be detected in blood platelets and there was no difference with detection in plasma. EGFRvIII RNA existed in both TEPs and plasma, but EGFR intracellular mutations cannot be detected in DNA of TEPs isolated from NSCLC. |
| Pubmed ID | 29922089 |
| Year | 2018 |
| Title | LncRNAs and EGFRvIII sequestered in TEPs enable blood-based NSCLC diagnosis. |
External Links
| Links for ZFAS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |