Basic Information
| LncRNA/CircRNA Name | lncRNA-ZNF281 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc |
| Sample | gastric tumor tissues,cell lines(AGS and SNU-1 ) |
| Expression Pattern | up-regulated |
| Function Description | The present study revealed that lncRNA-ZNF281 was upregulated, and that microRNA (miR)-124 was downregulated, in cancerous tissues compared with that in the paired adjacent healthy tissues of patients with gastric cancer. In addition, the expression levels of lncRNA-ZNF281 and miR-124 exhibited a significant inverse association. |
| Pubmed ID | 32194679 |
| Year | 2020 |
| Title | Long Non-Coding RNA-ZNF281 Promotes Cancer Cell Migration and Invasion in Gastric Cancer via Downregulation of microRNA-124 |
External Links
| Links for lncRNA-ZNF281 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |