Basic Information
| LncRNA/CircRNA Name | ZNF667-AS1 |
| Synonyms | NA |
| Region | GRCh38_19:56477250-56500666 |
| Ensemble | ENSG00000166770 |
| Refseq | NR_036521 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Microarray, western blot |
| Sample | cell lines(SiHa) |
| Expression Pattern | down-regulated |
| Function Description | the expression of LncRNA ZNF667-AS1 in cervical cancer was significantly lower than that in normal cervical tissues.the expression of LncRNA ZNF667-AS1 in cervical cancer tissues was lower than that in normal cervical tissues, which was consistent with that of TCGA.the expression of LncRNA ZNF667-AS1 was correlated with the total survival, tumor size and FIGO stage.Compared with the negative control group, the proliferation ability and cell cloning ability of cells with over-expressed LncRNA ZNF667-AS1 were significantly decreased, indicating that overexpression of ZNF667-AS1 inhibited the proliferation of SiHa cells. |
| Pubmed ID | 29243775 |
| Year | 2017 |
| Title | Independent prognostic Factor of low-expressed LncRNA ZNF667-AS1 for cervical cancer and inhibitory function on the proliferation of cervical canc |
External Links
| Links for ZNF667-AS1 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |