Basic Information
| LncRNA/CircRNA Name | ZXF1 |
| Synonyms | ACTA2-AS1, ZXF1, uc001kfo.1 |
| Region | GRCh38_10:88932390-88940820 |
| Ensemble | ENSG00000180139 |
| Refseq | NR_125373 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | LA tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | ZXF1 could function as an oncogene partly by sponging miR-634 and therefore regulating GRB2 expression in LA. |
| Pubmed ID | 32160453 |
| Year | 2020 |
| Title | Downregulation of long non-coding RNA ZXF1 restricts cell survival by targeting miR-634-GRB2 in lung adenocarcinoma |
External Links
| Links for ZXF1 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |