Basic Information
| LncRNA/CircRNA Name | circKIF4A |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Transwell assay, wound-healing assay, cell colony formation and flow cytometry |
| Sample | glioma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circKIF4A promoted Wnt5a expression by sponging miR-139-3p. Knockdown of circKIF4A inhibited the colony formation ability, migration and invasion, and promoted the apoptosis of glioma cells by regulating miR-139-3p. |
| Pubmed ID | 32268875 |
| Year | 2020 |
| Title | circKIF4A promotes tumorogenesis of glioma by targeting miR-139-3p to activate Wnt5a signaling |
External Links
| Links for circKIF4A | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |