Basic Information
| LncRNA/CircRNA Name | circ_0061140 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Dual luciferase reporter experiment and RIP |
| Sample | endometrial carcinoma tissues |
| Expression Pattern | differential expressed |
| Function Description | Here, hsa_circ_0061140 expression was modulated using functional assays and we found loss of hsa_circ_0061140 significantly restrained EC cells progression. Moreover, we revealed hsa_circ_0061140 could act as a molecular sponge for miR-149-5p. STAT3 was predicted as a downstream target gene of miR-149-5p. |
| Pubmed ID | 32224273 |
| Year | 2020 |
| Title | Hsa_circ_0061140 promotes endometrial carcinoma progression via regulating miR-149-5p/STAT3 |
External Links
| Links for circ_0061140 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |