Basic Information
| LncRNA/CircRNA Name | circFOXK2? |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Pancreatic Ductal Adenocarcinoma |
| ICD-0-3 | C25.3 |
| Methods | qPCR, Western blotting |
| Sample | Pancreatic Ductal Adenocarcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | circFOXK2 promoted cell growth, migration, and invasion and was involved in cell cycle progression and apoptosis. circFOXK2 contained multiple miRNA binding sites, functioning as a sponge for miR-942, which in turn promoted expression of ANK1, GDNF, and PAX6. |
| Pubmed ID | 32217695 |
| Year | 2020 |
| Title | CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA Binding Proteins and Sponging MiR-942 |
External Links
| Links for circFOXK2? | GenBank HGNC NONCODE |
| Links for Pancreatic Ductal Adenocarcinoma | OMIM COSMIC |