Basic Information
| LncRNA/CircRNA Name | circ_012515 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | non-small cell lung cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | In the cancerous tissues from NSCLC patients, NSCLC cells and gefitinib-resistant cell lines, the average expressions of hsa_circRNA_012515 increased significantly (P<0.01). Patients of stage III-IV, with lymph node metastases, had an overexpression of hsa_circRNA_012515. High expression of hsa_circRNA_012515 was associated with lower OS and shorter PFS, and it is closely related to the prognosis of the patients. |
| Pubmed ID | 32210630 |
| Year | 2020 |
| Title | hsa_circRNA_012515 Is Highly Expressed in NSCLC Patients and Affects Its Prognosis |
External Links
| Links for circ_012515 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |