Basic Information
| LncRNA/CircRNA Name | circPIP5K1A |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, nucleic acid electrophoresis, RNase R and Actinomycin D treatment. CCK-8, colony formation, EdU, transwell, TUNEL, flow cytometry, luciferase reporter, RIP and RNA pull-down assays |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circPIP5K1A, featured with closed-loop structure, was proved to be highly expressed in tissues and cells of GC. Loss-of-function assays depicted that silencing circPIP5K1A suppressed GC development. |
| Pubmed ID | 32190005 |
| Year | 2020 |
| Title | CircPIP5K1A facilitates gastric cancer progression via miR-376c-3p/ZNF146 axis |
External Links
| Links for circPIP5K1A | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |