Basic Information
| LncRNA/CircRNA Name | circMATR3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hypopharyngeal cancer |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | hypopharyngeal cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We found that circMATR3 was up-regulated in HSCC tissues, and abundant circMATR3 expression was markedly correlated with late T classification, advanced clinical stage, greater lymph node metastasis, and poor prognosis. Furthermore, knock-down of circMATR3 significantly inhibited proliferation, migration and invasion of HSCC cells, whereas silencing of circMATR3 induced cell apoptosis. |
| Pubmed ID | 32166857 |
| Year | 2020 |
| Title | Effect of up-regulation of circMATR3 on the proliferation, metastasis, progression and survival of hypopharyngeal carcinoma |
External Links
| Links for circMATR3 | GenBank HGNC NONCODE |
| Links for hypopharyngeal cancer | OMIM COSMIC |