Basic Information
| LncRNA/CircRNA Name | circ_0009910 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, colony formation, and Transwell assay |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0009910 was upregulated in HCC tissues and cell lines. Knockdown of circ_0009910 significantly inhibited the proliferation, migration, and invasion of HepG2 cells and suppressed tumor growth and metastasis in vivo. |
| Pubmed ID | 32141540 |
| Year | 2020 |
| Title | Circ_0009910 promotes proliferation and metastasis of hepatocellular carcinoma cells through miR-335-5p/ROCK1 axis |
External Links
| Links for circ_0009910 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |