Basic Information
| LncRNA/CircRNA Name | circ_0000388 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, western blot, RNA immunoprecipitation assay, and luciferase reporter assay |
| Sample | cervical cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0000388 expression in CC clinical samples was upregulated and this was correlated with unfavorable pathological indexes. Circ_0000388 remarkably enhanced the proliferation and metastasis of CC cells. Circ_0000388 overexpression dramatically impeded miR-337-3p expression and it was identified as a sponge of miR-337-3p. |
| Pubmed ID | 32119786 |
| Year | 2020 |
| Title | Circ_0000388 Exerts Oncogenic Function in Cervical Cancer Cells by Regulating miR-337-3p/TCF12 Axis |
External Links
| Links for circ_0000388 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |