Basic Information
| LncRNA/CircRNA Name | circ_0006282 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, western blot, CCK-8 assay, colony formation and transwell assays |
| Sample | gastric cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | over-expression of circ_0006282 was associated with tumor size, lymph nodes metastasis and TNM stage, but no obvious links with other pathological parameters. Knockdown of circ_0006282 inhibited the proliferation and metastasis ability of GC cells in vitro and suppressed the tumor growth in vivo. |
| Pubmed ID | 32099403 |
| Year | 2020 |
| Title | Circular RNA circ_0006282 Contributes to the Progression of Gastric Cancer by Sponging miR-155 to Upregulate the Expression of FBXO22 |
External Links
| Links for circ_0006282 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |