Basic Information
| LncRNA/CircRNA Name | circ_0010882 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, western blotting |
| Sample | gastric cancer cell lines and plasma |
| Expression Pattern | up-regulated |
| Function Description | We found that hsa_circ_0010882 expression was significantly upregulated in the plasma of GC patients and GC cell lines. In addition, GC patients with higher expression of hsa_circ_0010882 had significantly lower overall survival than patients with lower expression of hsa_circ_0010882. The proliferation, migration, and invasiveness of GC cell lines were inhibited following hsa_circ_0010882 knock-down, while GC cellular apoptosis increased. |
| Pubmed ID | 32096170 |
| Year | 2020 |
| Title | Circular RNA hsa_circ_0010882 promotes the progression of gastric cancer via regulation of the PI3K/Akt/mTOR signaling pathway |
External Links
| Links for circ_0010882 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |