Basic Information
| LncRNA/CircRNA Name | circRASSF2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | exosome | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | papillary thyroid cancer tissues, serum and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circRASSF2 was observed to be upregulated in PTC tissues and cell lines. Knockdown of circRASSF2 inhibited cell proliferation and promoted cell apoptosis in PTC cells. Importantly, we demonstrated that circRASSF2 was upregulated in serum exosomes from PTC patients. |
| Pubmed ID | 32059341 |
| Year | 2020 |
| Title | circRASSF2 Acts as ceRNA and Promotes Papillary Thyroid Carcinoma Progression through miR-1178/TLR4 Signaling Pathway |
External Links
| Links for circRASSF2 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |