Basic Information
| LncRNA/CircRNA Name | circRBM33 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Dual luciferase reporter assay, CCK-8, western blot |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | CircRBM33 was distinctly upregulated in GC specimens and cell lines and a close correlation between circRBM33 expression and clinical characteristics of GC was observed. After silencing circRBM33, the apoptosis of GC cells increased, while proliferation, migration, and invasion decreased. |
| Pubmed ID | 32044717 |
| Year | 2020 |
| Title | CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149 |
External Links
| Links for circRBM33 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |