Basic Information
| LncRNA/CircRNA Name | CASC9 |
| Synonyms | CASC9, ESCCAL-1, ESSCAL1, LINC00981 |
| Region | GRCh38_8:75223404-75324741 |
| Ensemble | ENSG00000249395 |
| Refseq | NR_103848 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | esophageal squamous cell carcinoma tissues, cell lines (KYSE30,KYSE150, TE-1, Eca-109,HEEpiC) |
| Expression Pattern | up-regulated |
| Function Description | CASC9 expression is independent Multivariate analysis showed prognostic indicators of overall survival and disease-free survival.inhibition of CASC9 can inhibit the proliferation, migration and invasion of ESCC. Abnormal CASC9 expression can regulate the expression level of markers EMT. |
| Pubmed ID | 29424900 |
| Year | 2018 |
| Title | LncRNA CASC9 promotes tumorigenesis by affecting EMT and predicts poor prognosis in esophageal squamous cell cancer. |
External Links
| Links for CASC9 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |