Basic Information
| LncRNA/CircRNA Name | circ_0061825 |
| Synonyms | circTFF1 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, western blot, RIP |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Circ-TFF1 and TFF1 were both upregulated and positively associated with each other in breast cancer. Knockdown of circ-TFF1 hindered breast cancer cell proliferation, migration, invasion and EMT in vitro and controlled tumour growth in vivo. |
| Pubmed ID | 31961997 |
| Year | 2020 |
| Title | Circular RNA hsa_circ_0061825 (circ-TFF1) contributes to breast cancer progression through targeting miR-326/TFF1 signalling |
External Links
| Links for circ_0061825 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |