Basic Information
| LncRNA/CircRNA Name | circABCC1 |
| Synonyms | circ_0000677 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | exosome | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, sphere-forming, transwell, and Western blot |
| Sample | colorectal cancer exosomes |
| Expression Pattern | differential expressed |
| Function Description | circ-ABCC1 was confirmed to facilitate CRC progression by activating the Wnt/?-catenin pathway. |
| Pubmed ID | 31960989 |
| Year | 2020 |
| Title | Exosomes from CD133+ cells carrying circ-ABCC1 mediate cell stemness and metastasis in colorectal cancer |
External Links
| Links for circABCC1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |