Basic Information
| LncRNA/CircRNA Name | circ_0014130 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, MTT assay or flow cytometry |
| Sample | non-small cell lung cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0014130 was abnormally highly expressed in NSCLC tissues and cells. After shRNA interfering circ_0014130 of NSCLC cells H1299 and A549, the NSCLC cell proliferation was inhibited and the cell apoptosis was promoted. |
| Pubmed ID | 31916848 |
| Year | 2020 |
| Title | Circ_0014130 Participates in the Proliferation and Apoptosis of Nonsmall Cell Lung Cancer Cells via the miR-142-5p/IGF-1 Axis |
External Links
| Links for circ_0014130 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |