Basic Information
| LncRNA/CircRNA Name | circACAP2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, CCK-8, colony formation assay and flow cytometry assay |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | CircACAP2 expression was prominently elevated in tumorous tissues. Functionally and mechanistically, circACAP2 promoted breast cancer proliferation and motility by sponging miR-29a/b-3p and modulating COL5A1. |
| Pubmed ID | 31863774 |
| Year | 2020 |
| Title | CircACAP2 promotes breast cancer proliferation and metastasis by targeting miR-29a/b-3p-COL5A1 axis |
External Links
| Links for circACAP2 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |