Basic Information
| LncRNA/CircRNA Name | circ_0016418 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, western blot, Transwell assay, CCk-8 |
| Sample | melanoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | The levels of circ0016418 and Yin Yang 1 (YY1) were up-regulated in skin melanoma tissues and cells. Knockdown of both circ0016418 and YY1 had suppressive effects on proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of skin melanoma cells. |
| Pubmed ID | 31862871 |
| Year | 2020 |
| Title | CircRNA_0016418 expedites the progression of human skin melanoma via miR-625/YY1 axis |
External Links
| Links for circ_0016418 | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |