Basic Information
| LncRNA/CircRNA Name | circ_0000285 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal cancer |
| ICD-0-3 | C32 |
| Methods | qPCR, western blot |
| Sample | laryngeal cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Hsa_circ_0000285 expression was found to be upregulated in laryngocarcinoma samples compared with adjacent tissues. The function assays showed that the inhibition of the cell proliferation was induced via knockdown of hsa_circ_0000285 in laryngocarcinoma in vitro, while the promotion of cell apoptosis was induced via the knockdown of hsa_circ_0000285 in laryngocarcinoma in vitro. |
| Pubmed ID | 31858548 |
| Year | 2020 |
| Title | Circular RNA hsa_circ_0000285 acts as an oncogene in laryngocarcinoma by inducing Wnt/?-catenin signaling pathway |
External Links
| Links for circ_0000285 | GenBank HGNC NONCODE |
| Links for laryngeal cancer | OMIM COSMIC |