Basic Information
| LncRNA/CircRNA Name | circ_0000267 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, CCK-8 assay, BrdU assay, scratch healing assay, and transwell assay |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0000267 showed a significant upregulation in GC tissues and cell lines, and its high expression level was extremely linked to the increased tumor diameter and local lymph node metastasis. Circ_0000267 overexpression accelerated GC cell proliferation, metastasis, and EMT processes, while knocking down circ_0000267 led to the opposite effect. |
| Pubmed ID | 31845519 |
| Year | 2020 |
| Title | Circ_0000267 promotes gastric cancer progression via sponging MiR-503-5p and regulating HMGA2 expression |
External Links
| Links for circ_0000267 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |