Basic Information
| LncRNA/CircRNA Name | circCDYL |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR |
| Sample | colon cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | We found circCDYL was generally decreased while miR-150-5p was increased in colon cancer tissues in parallel with the para-carcinoma tissues. In circCDYL-transfected SW480 and SW620 cells, circCDYL decreased viability and promoted apoptosis with down-regulation of c-Myc and cyclin D1, up-regulation of p53, and cleavage of caspase-3 and PARP. |
| Pubmed ID | 31829306 |
| Year | 2019 |
| Title | circCDYL/microRNA-105-5p participates in modulating growth and migration of colon cancer cells |
External Links
| Links for circCDYL | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |