Basic Information
| LncRNA/CircRNA Name | circAMOTL |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR |
| Sample | cervical cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | circAMOTL1 and its host gene AMOTL1 were both upregulated in cervical cancer tissues and closely correlated with poor prognosis of cervical cancer. Gain- or loss-of-function assays and in vivo experiments demonstrated that AMOTL1 promoted cervical cancer cell growth both in vitro and in vivo. |
| Pubmed ID | 31812104 |
| Year | 2019 |
| Title | circAMOTL1 Motivates AMOTL1 Expression to Facilitate Cervical Cancer Growth |
External Links
| Links for circAMOTL | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |