Basic Information
| LncRNA/CircRNA Name | circMYC |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | melanoma tissues |
| Expression Pattern | up-regulated |
| Function Description | Our current study demonstrated that human circMYC was obviously upregulated in human melanoma tissue. Furthermore, circMYC promoted the proliferation of human melanoma cells and Mel-CV cells. The expression of circMYC can repress Mel-CV cell glycolysis and LDHA activities in the in vitro glycolysis and lactate production evaluations. |
| Pubmed ID | 31811601 |
| Year | 2020 |
| Title | CircMYC Regulates Glycolysis and Cell Proliferation in Melanoma |
External Links
| Links for circMYC | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |