Basic Information
| LncRNA/CircRNA Name | circ_0046600 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Dual luciferase reporter assay |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | The expression level of hsa-circ-0046600 in HCC tissue was significantly higher than that in adjacent normal tissue (P < 0.05) and was associated with tumour size, TNM stage and pathological vascular invasion. Moreover, the downregulated expression of hsa-circ-0046600 significantly inhibited the migration of HepG2 and SK-HEP-1 cells. |
| Pubmed ID | 31807009 |
| Year | 2019 |
| Title | Emerging Roles Of hsa-circ-0046600 Targeting The miR-640/HIF-1? Signalling Pathway In The Progression Of HCC |
External Links
| Links for circ_0046600 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |