Basic Information
| LncRNA/CircRNA Name | circTUBB |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | other |
| Sample | colorectal cancer cell lines |
| Expression Pattern | differential expressed |
| Function Description | rs25497 in circTUBB was significantly associated with colorectal cancer risk in a Chinese population after false discovery rate (FDR) correction [odds ratio (OR) = 1.78, 95% confidence interval (CI) = 1.44-2.21, P????.42????10-7, PFDR????.80????10-5] and even reached significance in a genome-wide association study (GWAS) under the dominant model (P????.28????10-8). |
| Pubmed ID | 31797002 |
| Year | 2019 |
| Title | Genetic variants in circTUBB interacting with smoking can enhance colorectal cancer risk |
External Links
| Links for circTUBB | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |