Basic Information
| LncRNA/CircRNA Name | circ _0137439 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR |
| Sample | bladder cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We found that hsa_circ_0137439 was significantly upregulated in bladder cancer samples. Moreover, increased expression of hsa_circ_0137439 was correlated with higher tumor stage, higher tumor grade, higher lymph node status, and history of muscle-invasive bladder cancer (MIBC). Additionally, hsa_circ_0137439 in urine supernatant could serve as an independent prognostic predicator of recurrence-free survival and overall survival for patients with bladder cancer. |
| Pubmed ID | 31777254 |
| Year | 2020 |
| Title | Identification of urinary hsa_circ _0137439 as potential biomarker and tumor regulator of bladder cancer |
External Links
| Links for circ _0137439 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |