Basic Information
| LncRNA/CircRNA Name | circ_0001658 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, CCK8 assay, colony formation assay, flow cytometry, and transwell assay |
| Sample | osteosarcoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Compared with adjacent tissues, circ_0001658 displayed a significantly higher expression in OS tissues. Circ_0001658 could facilitate the proliferation, migration, and invasion of OS cells and impede apoptosis by sponging miR-382-5p. Circ_0001658 promotes the proliferation and metastasis of OS cells via modulating miR-382-5p/YB-1 axis. |
| Pubmed ID | 31758574 |
| Year | 2020 |
| Title | Circ_0001658 promotes the proliferation and metastasis of osteosarcoma cells via regulating miR-382-5p/YB-1 axis |
External Links
| Links for circ_0001658 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |