Basic Information
| LncRNA/CircRNA Name | circFMN2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | exosome | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | colorectal cancer tissues, serum and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circFMN2 was found to be significantly up-regulated in CRC tissues and cell lines. Moreover, knockdown of circFMN2 significantly inhibited cell proliferation and migration in vitro. Importantly, we demonstrated that circFMN2 was up-regulated in serum exosomes from CRC patients. |
| Pubmed ID | 31738400 |
| Year | 2019 |
| Title | A novel circFMN2 promotes tumor proliferation in CRC by regulating the miR-1182/hTERT signaling pathways |
External Links
| Links for circFMN2 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |