Basic Information
| LncRNA/CircRNA Name | circGRAMD1B |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, fluorescence in situ hybridization, Dual luciferase reporter assay, RNA immunoprecipitation, RNA pull-down assay, and rescue experiments |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | circGRAMD1B expression was downregulated in GC tissues and cell lines. Functionally, circGRAMD1B acted as an anti-oncogene and inhibited the proliferation, migration, and invasion abilities of GC cells. |
| Pubmed ID | 31719211 |
| Year | 2019 |
| Title | Circular RNA circGRAMD1B inhibits gastric cancer progression by sponging miR-130a-3p and regulating PTEN and p21 expression |
External Links
| Links for circGRAMD1B | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |